About halfway through the game, the Brainiacs start taking notice of you, and begin to send specialized killers after you. Extensively modified using ADAM and robotics, these psychos have only one purpose in "life": killing you.


  • Level 1: Increased Damage to Assassins
  • Level 2: Increased Friendly Security Damage
  • Level 3: Increased Damage to Assassins
  • Level 4: Increased Friendly Security Damage
  • Level 5: Dark Vision Gene Tonic


Think of the Assassins from Assassin's Creed, crossed with a cybernetic Grim Reaper.



Produces dual swords or pistols from his sleeves to attack you with.


Grabs a nearby Splicer and then the Assassin's hood leans forward to envelope the head of his victim. After some grisly noises, the Assassin has restored his health and the splicer is headless. Interrupt this before he is finished to prevent him from regaining his head.


Turns invisible for a short period of time.


The Assassin has agility that would put a Big Sister to shame. They are fast and strong, capable of jumping great distances, and running up walls and across ceilings.

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