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I'm too timid to try it out...-Namelesswalaby 11 Feb 2010 2333hrs
What's to lose? Save, try it, reload if you are not happy. After 4 playthroughs, I decided to play the whole game with nothing but the drill and plasmids. I was nervous when facing my first Big Daddy, and was amazed how easy it was to kill him with the drill and it continues to be easy throughout the game. It is by far the easiest way to kill the big foes while losing minimal health. I had previously been laying out traps, sniping and running, and basically getting blown up by him every time, but when you close in with the drill (and maybe a side order of Electric Bolt), you often lose no health at all. The drill also can take down Big Sisters and Alphas pretty easily. Any foe, such as these, which you are unlikely to kill with one running smash, you are better off approaching them with the drill going and continuing to press forward.
Splicers can be handled early on with Electric Bolt and Incinerate, and once you get Hypnotize, you can even handle the crowds at Little Sister feedings with just plasmids.
I have to say, though, that I was not impressed with the amount of reduction in EVE used with Drill Specialist.
It's awesome until you run out of fuel.--Kamikaze14 18:58, April 4, 2010 (UTC)