In February 15th, the Smithsonian created a voting poll for The Art of Video Games, a new exhibit that focuses on the creativity and innovation of video games through 40 years, or in this case 5 eras, of history. Despite a tough voting descision between other nominations, BioShock has won the nomination for Era 5: Xbox 360's Action category, with Ken Levine for Story and Creative Direction, and Scott Sinclair for Art Director.
You can go to the Smithsonian's site for more information on the exhibit
You can also view the rest of the winners through the PDF here:
The Smithsonian Art of Video Games exhibit opens March 16th, 2012- September 30th, 2012